melatonin

🌙 ARTICLE 1


Melatonin: the natural sleep signal


Melatonin is a hormone naturally produced by the body, primarily in response to darkness. It plays a key role in regulating the sleep-wake cycle.


Often called the “night hormone”, it acts as a biological signal telling the body that it’s time to slow down.


When exposure to artificial light, stress, or an irregular rhythm disrupts this signal, falling asleep can become more difficult.


An appropriate supplemental intake of melatonin contributes to:

  • 🌙 To reduce the time it takes to fall asleep

  • ⏰ To regulate the biological rhythm

  • ✈️ To mitigate the effects of jet lag


Integrated into a structured evening routine, melatonin can accompany the natural transition to sleep, without abrupt effect, respecting the body's physiological mechanisms.

🔬 ARTICLE 2


Melatonin: scientific data and physiological role


Melatonin is synthesized from tryptophan via serotonin. Its secretion naturally increases in the evening, in response to darkness.

🧠 1. Regulation of the circadian rhythm


Melatonin acts on MT1 and MT2 receptors located in the suprachiasmatic nucleus, the center for regulating the biological clock.


She participates in:

  • Synchronization of the sleep-wake cycle

  • The modulation of circadian rhythms

  • Adapting to changes in brightness


📚 Reference:

Arendt J. (1995). Melatonin and the Mammalian Pineal Gland . Chapman & Hall.

Brzezinski A. (1997). Melatonin in humans . New England Journal of Medicine.

🌙 2. Melatonin and falling asleep


Clinical studies have shown that melatonin can help reduce the time it takes to fall asleep, particularly in cases of circadian rhythm disruption.


📚 Reference:

Ferracioli-Oda E. et al. (2013). Meta-analysis: Melatonin for the treatment of primary sleep disorders . PLOS ONE.

✈️ 3. Time difference


Melatonin also helps to alleviate the subjective effects of jet lag.


📚 Reference:

Herxheimer A., ​​Petrie KJ (2002). Melatonin for the prevention and treatment of jet lag . Cochrane Database of Systematic Reviews.

📌 Claims authorized in Europe (EFSA)


Melatonin contributes to:

  • to reduce the time it takes to fall asleep

    (beneficial effect obtained with a consumption of 1 mg before bedtime)

  • to mitigate the effects of jet lag

    (beneficial effect obtained with a minimum consumption of 0.5 mg on the first day of travel and subsequent days)


Regulation (EU) No 432/2012.

🌙 Interest in an evening meal plan


Melatonin does not artificially induce sleep:

It acts as a chronobiological signal , facilitating the natural transition to sleep when the environment and lifestyle are consistent.


Combined with relaxing plants and micronutrients that support nervous system balance, it fits into a holistic approach to nighttime well-being.

Conclusion: A natural and well-documented approach to regaining more peaceful nights

In a daily life marked by stress and mental overload , it becomes essential to adopt solutions that respect the body's balance. Thanks to the combination of plants traditionally used for relaxation and micronutrients studied for their role in nervous system balance, Nubia embodies an approach that is both natural and informed by science .

Click here to discover how to integrate Nubia into your evening routine and accompany your nights towards more calm and regularity.

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